Abstract 194: Impact Of Psoriasis On The Outcomes Of St-elevation Myocardial Infarction From The Nationwide Readmission Database

Background: Psoriasis is a chronic inflammatory disease which causes atherosclerosis. There is conflicting data regarding the association between psoriasis and the development of cerebrovascular diseases with increased mortality. There is also limited data about the outcomes of the psoriatic patients presenting with ST-elevation myocardial infarction (STEMI).

Methods: We queried the Nationwide Readmissions Database (years: 2016-2019) using ICD-10 codes for patients with a primary diagnosis of STEMI who underwent primary percutaneous coronary intervention (PCI). Patients were classified into two groups according to the presence of psoriasis. Outcomes included in-hospital mortality, index admission compilations, 90-day readmission rate, and causes of readmissions.

Results: A total of 52,796 patients with STEMI underwent PCI including 308 with psoriasis and 52,488 with no psoriasis. Mean age and gender were similar between both groups. Psoriasis patients had more prevalence of obesity, diabetes mellitus (DM) obstructive sleep apnea (OSA) and depression. In-hospital mortality rate was not significantly different between the two groups. The length of stay and the total charges were higher in the psoriasis group (Table 1). During the index admission, the most common complications were not different. However, hemorrhagic anemia was higher in the psoriatic group. There were 6,896 (13.1%) readmission in the non-psoriasis group compared to 28 (9.1%).

Conclusion: Patients with psoriasis had higher prevalence of cardiovascular risk factors including obesity, OSA, and DM, without a significant increase in the in-hospital mortality and the 90-day readmission rate.